E Biogen Idec Achieves Positive Interim Results In Treating Early Stage Alzheimer’s Patients

Biogen Idec (BIIB) reported on December 2, 2014 that it had achieved positive results in an early study in patients with Alzheimer's. Alzheimer's is a brain deterioration in mental status that progressively gets worse over time. Alzheimer's affects memory, behavior, and thinking which can severely impact a patient's life. Biogen Idec had started a study to test the efficacy of the BIIB037 compound in patients with Alzheimer's. The study recruited 200 patients and is testing BIIB037 against a placebo compound. 

The trial isn't quite finished yet but additional results will be presented early next year. Shares of Biogen rose up as high as 6% on the news that their compound BIIB037 was able to reduce beta amyloid — also known as plaques– in the brain, which are believed to be  the main cause for developing Alzheimer's disease.

The early-stage study showed that BIIB037 was able to both reduce beta amyloid proteins in the brain and measurably improve patients' cognitive ability within the 54-week period. Most impressive is the results indicating that the company's drug removes amyloid plaques in a dose dependent manner. That means the higher the dosage of BIIB037 given to a patient, the more beta amyloid plaques are removed in the process. 

Although these interim results are promising, more testing will be needed in a planned, larger late-stage trial to determine efficacy of the drug.

Biogen stock was up almost 6% today on the news. The stock is up almost 22% in the past year.

 

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